On March 25th, 2022, the National Cooperation Network for Higher Educations Institutions in Mathematics and Natural Sciences (MIPANet) held an annual meeting with a hybrid model at the Faculty of Mathematics and Natural Sciences, Universitas Sam Ratulangi. This meeting aims to increase the relationship between Higher Education Institutions in the Mathematics and Natural Sciences and conjoined with the National Seminar on Applied-Science (SEMNAS-SINTA) VI. With the theme of "Optimization of Post-Pandemic Environment Arrangements and Entrepreneurs," deans from numerous faculties participated in the meeting. They included Prof. Dr. Astin Lukum, M.Si as the Dean of FMIPA Universitas Negeri Gorontalo, the Faculty of Science and Mathematics, the Faculty of Biology, and the Faculty of Science and Technology, which are united in the National Cooperation Network for Mathematics and Natural Sciences Educational Institutions. The National Cooperation Network for Higher Educations Institutions in Mathematics and Natural Sciences (MIPANet) supports scientific development and cooperation as a basic framework for contributing to national development.